It's not just the mother's age that matters. According to new research, men's biological clocks are ticking, too. Older fathers may put their infants — and partners — at risk for pregnancy complications.
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It's 8 a.m. on your 35th birthday and your mother has already called you three times. You want to sleep longer, but she persists. You call her back; she answers after the first ring.
"Sweetie," she says, out of breath. "I was just in the kitchen making breakfast and — you won't believe this — I cracked open an egg with two yolks inside. Do you know what that means?"
Of course you know what it means. According to modern fertility folklore, pregnancy might be on the way. But why doesn't your mother ever call your 40-year-old brother with these brilliant fertility revelations?
Older male fertility: should we be worried?
Most couples trying to conceive (and enthusiastic mothers-in-law) know that decades of research point to a woman's age of 35 as the point in which women may begin to experience age-related pregnancy complications.
The scientific interest in women is intuitive — they play the most obvious role in the pregnancy.
Little attention, however, has been placed upon male fertility. This information gap can be rather simply illustrated by Google search data: Issues surrounding female age and fertility are Googled almost 4 times more often than male age and fertility.
According to a recent Rutgers study published in Maturitas, a medical journal covering midlife and post-reproductive health, this lack of attention is a mistake.
The study, which reviewed 40 years of research on the effects of parental age on fertility, found links between older fathers and a variety of infant health risks.
Infants born to fathers older than 45 have a higher risk of premature birth, low Apgar scores ( based on the well-being test conducted immediately after the baby’s birth that ranks the infant based on appearance, pulse, grimace, activity and respiration) and low birth weight. They also have a higher risk of newborn seizures and late stillbirth, according to the study.
Findings presented in the study also pointed to a correlation in the presence of schizophrenia and autism in people with fathers older than 50, something that a recent study in the journal Biological Psychiatry pointed to as well, along with birth defects such as congenital heart disease and cleft palate.
Many of these issues occurred regardless of the age of female partners, who were also more likely to experience increased pregnancy complications such as gestational diabetes, preeclampsia and preterm birth after conceiving a child with an older man.
"Although it is well documented that children of older fathers are more likely to be diagnosed with schizophrenia — one in 141 infants with fathers under 25 versus one in 47 with fathers over 50 — the reason is not well understood," said the study's author Gloria Bachmann, director of the Women's Health Institute at Rutgers Robert Wood Johnson Medical School in New Jersey.
What does all of this mean?
Bachmann said these findings have to do with male sperm. As people lose muscle strength and endurance with age, sperm also lose fitness over the life cycle, she said, which affects both the likelihood of conception and the prevalence of complications if conception does occur.
The definitive age in which men are more likely to negatively influence pregnancy is still unclear. According to the report, it could be anywhere from 35 to 45. But the correlation is there, and researchers are urging others to take a closer look.
"The disparity between the social interpretation of men's and women's fertility and role in reproduction speaks volumes regarding our assumptions about gender roles, reproduction and family planning," the study said.
It also notes that the issues it addresses are not widely known throughout the medical and social communities and urges health care providers to alert men to the risks associated with higher paternal ages.
The scientists' advice goes out not just to men who are considering having a baby with their wife or girlfriend: Sperm banks, the researchers pointed out, should adjust their age limits for donations, too.
Lilibet Diana and other royal babies
Prince Harry and Meghan Markle announced the birth of their second child, a baby girl. Here are a few other British royal babies who've smiled for the camera.
Image: picture-alliance/dpa
Another reason to smile: the birth of their daughter Lilibet Diana
"It is with great joy that Prince Harry and Meghan, The Duke and Duchess of Sussex, welcome their daughter, Lilibet 'Lili' Diana Mountbatten-Windsor, to the world," the couple's press secretary said Sunday, after the announcement of the June 4 birth. The new baby is named after Queen Elizabeth and the late Diana, Princess of Wales, Harry's mother. Official pictures have not yet been released.
Image: Chris Jackson/Getty Images
Archie Harrison Mountbatten-Windsor
Meghan and Prince Harry's first child, Archie Harrison, was born on May 6, 2019. In the image shown here, the couple revealed their two-day-old son to the public, with the proud new mother declaring that the baby was "a dream." Archie is the seventh in line to the throne.
Image: Reuters/D. Lipinski
Prince Louis of Cambridge
Prince William and Kate introduced their third child to the world seven hours after his birth on April 23, 2018. While the boy was born on St. George's Day, the Duke and Duchess of Cambridge had to find another name for the fifth-in-line to the throne, as George is the name given to his older brother. They picked Louis Arthur Charles, and he will be known as Prince Louis.
Image: Reuters/J. Stillwell
Third in line to the throne
Kate Middleton, Duchess of Cambridge, gave birth to Prince William's first child on July 22, 2013. Officially called George Alexander Louis, Prince George became a big brother on May 2, 2015. The boy is third in line to succeed his great-grandmother, after his grandfather Charles and his father.
Image: Reuters
Fourth in line, Princess Charlotte
George's little sister, Princess Charlotte Elizabeth Diana, was born on May 2, 2015. Her name, which honors both her grandmother and great-grandmother, was announced two days later. This photo shows her at the age of one in 2016. Following changes in the rules of succession privileging male heirs, Princess Charlotte remains fourth in line to the throne, even though she now has a baby brother.
Image: picture-alliance/dpa/Hrh The Duchess Of Cambridge/Han
Cheerful Queen
These happy chubby cheeks belong to none other than Queen Elizabeth II. She is in the arms of her mother Elizabeth, the Duchess of York. Her father was the future King George VI. Elizabeth II's birth was a difficult one: The heiress to the throne was finally delivered via C-section on April 21, 1926. She grew up with her younger sister Margaret (1930-2002). Today, she is 92 years old.
Image: picture-alliance/dpa
His Royal Highness, in diapers
This young boy was born on June 10, 1921. At the time, Philip, Duke of Edinburgh didn't realize that about 25 years later he would be asking the hand of a future queen in marriage: Elizabeth II. Philip's father had already arranged a meeting with the then 13-year-old heiress to the throne in 1939. At the time, Philip was still a student at the Royal Naval College. He died on April 9, 2021.
Image: picture-alliance/dpa
Do you recognize this one?
Charles Philip Arthur George, better known as Prince Charles, was born on November 14, 1948. When he was four years old, his mother, Elizabeth II, ascended the throne. As the eldest child, Charles is the royal heir and Duke of Cornwall.
Image: picture-alliance/dpa
Princess of hearts
This baby would later become royal. Lady Di was born on July 1, 1961. In 1981, she married Prince Charles under the eyes of some 750 million television viewers worldwide. The failure of their marriage would be just as publicized. Diana's death in a car accident on the night of August 31, 1997 would be followed by another media frenzy. Her fans still mourn her today.
Image: picture-alliance/dpa
A smiling Prince William
Prince William Arthur Philip Louis Mountbatten-Windsor was born on June 21, 1982 in London. After their parents separated in 1992, William and his brother Harry lived alternately with Princess Diana in London's Kensington Palace or with their father and grandmother Elizabeth II at the Royal Court.
Image: picture-alliance/dpa
Harry, prince popular
His real name is Prince Henry Charles Albert David Mountbatten-Windsor. But the world prefers to simply call him Prince Harry. The sandy-haired baby was born on September 15, 1984. Harry's excessive partying as a teenager would later make tabloid headlines. He managed to get rid of his bad-boy image, and later married Meghan Markle. They now have children of their own.