Police and veterinarians managed to subdue the two Bengal tigers - named Radjah and Dehli - after several hours on the loose on Saturday in the village of Oldeberkoop in the north of the Netherlands.
"Careful work by a dog catcher and a vet appears to have tranquilised both tigers. Now checking if they're sleeping deeply," local police officer Jan Graafstra said in a tweet.
Although an earlier effort to tranquilize one of the big cats failed, police said residents were never in danger.
The animals fled the Felida center, a shelter that takes in big cats from circuses and zoos.
Dutch news agency ANP reported the tigers had escaped through a gate that had been accidently left open.
The center tends to the animals before moving some of them to a larger shelter in South Africa.
Radjah and Dehli had been acquired from a zoo in Germany that could no longer care for them.
Lions, tigers, bears, a hippo and other zoo animals have escaped from a zoo in Georgia's capital, Tbilisi, after heavy rainfall and strong winds destroyed their enclosures. At least eight people died in the flooding.
Image: Reuters/B. GulashviliTigers, lions, bears, a hippopotamus and other animals have escaped from a zoo in Georgia's capital, Tbilisi, after heavy rain and strong winds destroyed their enclosures overnight.
Image: Reuters/B. GulashviliAt least eight people were killed in the flooding, including three zoo employees, with 10 people remaining unaccounted for. Residents of the capital have been advised to stay inside as it is unclear how many animals are still roaming free.
Image: Reuters/I. GedenidzeEarlier on Sunday a hippo was cornered in one of Tbilisi's main squares. The animal was subdued with a tranquilizer gun.
Image: Reuters/B. GulashviliBears were among some of the animals to escape their destroyed enclosures when flooding hit the Georgian capital overnight. Some other animals have been recaptured, but helicopters continue to circle the city looking for the zoo's prized exhibits.
Image: Reuters/Georgian Prime Minister`s Office/B. GulashviliOne of zoo's bears, which escaped early on Sunday morning, has been swimming in a flooded Tbilisi street.
Image: Reuters/Georgian Prime Minister`s Office/B. GulashviliThe Vere river, which flows through Tbilisi, was turned into a torrent sweeping dozens of shacks and cars downstream.
Image: Reuters/B. GulashviliThe high water turned inner-city streets and squares into raging streams that were strewn with debris, including rubbish and fallen trees.
Image: Reuters/I. GedenidzeIn the city of 1.2 million, thoroughfares were covered with a thick layer of mud and hundreds of fallen trees. Scores of people have been left without shelter and thousands without electricity or clean water.
Image: Reuters/I. Gedenidze cw/sms (AFP, Reuters)