The brain is the most complex machine. It's misunderstood, does go wrong. Marco Magrini has written a "user's manual."
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DW: You've written possibly one of the hardest things: A user's manual for the brain. There's so much we don't know about the brain, and so much where experts disagree. Clearly, that fascinates you. Why?
I'm fascinated by the fact that the human brain can produce Bach's preludes and fugues, and that it can produce Leonardo da Vinci's works, or Hegel's thinking.
My fascination started when I was 18, because all of a suddenly I turned out to be a good student. I hadn't been a good student up until then. I'd had attention deficit disorder and I failed twice at high school.
Then, all of a sudden at 18 I turned out to be good at writing and studying, and that surprised me.
All through my life I have wondered what would have been if that disorder hadn't stopped by itself. It's a genetic condition, so I was lucky to have it solve itself. And that's where my fascination with the brain started.
Most of us only tend to think about the brain when things go wrong. And there's so much that can go wrong that it's become common for us to talk about a "spectrum" of mental conditions. You say, for instance, that brain illnesses are unique to each individual — that no two phobias are the same.
Exactly. We talk about an autistic spectrum because the manifestations are so different from one another. It's really hard to pinpoint the problem. There's also a lot of talk about comorbidity — having more than one disease at the same time, overlapping. That's why it can be so wildly complicated.
But because of the emergence of this — I'll call it a philosophy of spectrums — in mental illness, some people say it's led to people feeling they can self-diagnose. In a sense, it allows them to put themselves on a spectrum. Especially among young people there is a feeling that they have been trained to think of themselves in mental illness categories. How do you see that? We've got this growing awareness of the diversity of mental health and, at the same time, a means for people to sort of construct their own personalized conditions. Isn't there a danger in that?
Yes, self-diagnosis is risky. You cannot ask Wikipedia to solve your mental problems because it's quite complicated. At the same time, there are a few mental conditions where, if the patient is aware of the nature of their illness, it can be a first step towards an easing of the effects of the illness.
I'm thinking of borderline personality disorder, for instance. It can help if you're aware that you have it. So, I feel people should know the basics.
Seven facts about brain injuries
Playing through pain is widely seen as a good quality for an athlete to have. However, studies have shown that this can have consequences for one's health. NFL players have been known to die from the effects of CTE.
Image: picture alliance/AP Photo/G.J. Puskar
The NFL's first CTE diagnosis
"Iron Mike" Webster won four Super Bowls as a center for the Pittsburgh Steelers in the 1970s. However, after his career ended, the many hits to the head that he had received as a football player took their toll on his health. He died in 2002 at the age of just 50. After his death, Webster was diagnosed as having had chronic traumatic encephalopathy (CTE), a neurodegenerative disease.
Image: picture alliance/AP Photo/G.J. Puskar
A Hollywood film
Bennet Omalu, a forensic neuropathologist (pictured above, second from left) was the first to diagnose CTE in Webster and other former NFL players. He continued his research despite widespread and strong resistance to his findings. In 2015 director Peter Landesmann (above, right) directed the film "Concussion," in which actor Will Smith (left) played Omalu.
Image: picture alliance/AP Photo/M.S. Gordon
Gradual changes to the brain
Symptoms such as loss of speech, depression and dementia, which can be an indication of CTE, were first observed in boxers decades ago. Repeated blows to the head release the tau protein which accumulates in the brain. Those affected can experience changes to their personality, problems with aggression and even become susceptible to thoughts of suicide.
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Suicide and a final wish
Between 2008 and 2015 Terry Long, Tom McHale, Jovan Belcher, Adrian Robinson and Junior Seau were among the former NFL players who committed suicide. In 2011, Dave Duerson, a former safety, shot himself through the heart instead of in the head. In his suicide note he asked that his brain be examined to see if he had CTE. Doctors found clear signs that he had had the disease.
Image: picture-alliance/AP Photo/S. Walsh
The biggest stage
Head injuries occur in soccer as well. In the final of the 2014 World Cup in Rio de Janeiro, German midfielder Christoph Kramer was knocked out. He soldiered on for 14 minutes after the injury, which was a big risk, because a second hit shortly afterwards increases the danger of long-term damage. Even now, there is no universally agreed procedure for diagnosing brain injuries on the sidelines.
Image: picture alliance/dpa/T.Eisenhuth
Risk varies by position
Brain injuries in soccer tend to occur when two players clash heads when going for ball or as the result of an elbow to the head. A recent study by the Federal Institute of Sports Sciences has found that the risk of head injury in soccer varies according to a player's position. Defenders are most at risk, followed by midfielders and strikers. The risk is by far the lowest for goalkeepers.
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Which is the worst sport for concussions?
A study conducted by the Federal Institute for Sports Sciences, showed that rugby players are at the highest risk among athletes of suffering concussion. They are followed by American football players, ice hockey players and basketball players. Brain injuries are not as common in soccer, but in Germany, where it is the biggest sport, in absolute terms, it is where the most concussions occur.
Image: Getty Images/D. Rogers
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We are our brains. And a brain should know that a brain is not static — it's not immutable. It keeps changing. This is true of mental problems, malfunctions. And it's true of functioning brains. You can learn new things, or you can correct bad habits, even if they've become dependences. You can improve your memory. People should know that.
In your book, you mention some of the "imaginary illnesses" that have cropped up over the years. Things like the idea of homosexuality as a personality disorder, or "drapetomania," an idea from the 1800s that suggested slaves who ran away had a personality defect.
Isn't that funny! [Ed. Magrini means funny in a sad way.]
It is very funny. But if we're talking about influencing the way that our minds work, those wrong ideas about the brain make me wonder about the people who come up with them. For instance, the American surgeon Samuel A. Cartwright, who invented drapetomania. Did he truly believe that because he didn't understand the brain, or was he trying to manipulate other people's lack of understand about the brain?
Well, this is an apt topic if you think of fake news. What is fake news? A complicated entrenchment of false memories and several kinds of biases, like confirmation bias, where you interpret the news you receive as a confirmation your prejudices.
We know that false memories can be planted in people's minds via social media. This is a serious problem. Because memory is reconstructive. It's not a film that plays frame-by-frame. It's more like a detective, connecting different things that reside in different places. So, it's very easy to have false memories. And every brain, not just those effected by some kind of disturbance, can malfunction in this way.
Artificial Intelligence – Hype and Hysteria
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So speaking of bias, what about bias in technology, like artificial intelligence or machine learning? If there's still so much for us to understand about the brain, isn't it too soon to be making brain emulations such as these? Shouldn't we first understand the brain better to help us make truer emulations of the brain? Or are the biases true in themselves, because humans are biased and quite often wrong?
Brain emulations have been quite successful — up to a point. But we have not solved the mystery of intelligence.
So I can't say whether we should stop researching this, because researchers are doing statistically beautiful things. There are new trends in emulating the six layers of the cerebral cortex, and in hardware, neuromorphic chips.
But artificial intelligence is a bit overhyped. And I don't buy the idea that AI, in its current form, will turn into a conscious thing anytime soon.
It may happen, but not for a long time.
Marco Magrini is the author of "The Brain: A User's Manual — A simple guide to the world's most complex machine," which was originally published in Italian as "Cervello. Manuale dell'utente." It's been translated into French, Polish, Portuguese, and an English translation, which is published by Short Books in the UK.
8 ways to prevent dementia
The exact causes for Alzheimer's and other neurodegenerative diseases are unknown. But new WHO guidelines state that exercising, eating healthy, and staying mentally fit can help protect you.
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Losing weight
Those who are overweight should definitely do something about their diet and go to the gym. Obesity is a key factor in developing dementia. More excercise improves blood circulation and makes for a healthier metabolism.
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A Mediterranean-style diet
A healthy diet — rich in vegetables, salads and vegetable fats — has a positive effect on your blood vessels. Epidemiological studies show that people who lower their risk of a heart attack or stroke are also likely to develop dementia later than people eating food high on cholesterol.
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Get your move on!
Physical activity puts the blood vessels to use and is therefore good against dementia. It also directly helps the nerve system: The brain ultimately controls the body and receives stimulus back from the nerves in the muscles. The ability to keep one's balance and orient oneself improves — as does the memory.
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Quit that vice!
It has never been easier to quit smoking: It's prohibited almost everywhere and fewer and fewer people are lighting up. This also reduces the incentive to smoke in company. To put it bluntly: Nicotine is a nerve poison! It also increases the risk of circulatory diseases, which means less oxygen gets to the brain. And that in turn increases the dementia risk.
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Alcohol is pure poison
Alcohol is a nerve agent, too. In higher doses it directly damages the brain. Even in lower concentrations it increases the risk of dementia, by increasing the risk of cardiovascular diseases and damaging essential organs.
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Check your blood pressure
Keeping your blood pressure under control is an essential part of dementia prevention. Cardiovascular diseases are often linked to different forms of dementia. You can decrease your blood pressure through sports, healthy nutrition and abstaining from smoking or drinking. However, some people need to take additional medication to reach their blood pressure targets. Talk to your doctor!
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Stay mentally active
Any form of mental activity keeps the brain going. But it's not just about solving puzzles or learning things by heart. Social contacts are much more important, since they are challenging and help maintain memory. So stay in touch with your friends, do things together or organize community events!
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The best of all worlds: Dancing
Music, company, exercise and body control will keep you young and healthy! There is probably nothing better to prevent dementia than a regular stint on the dance floor. But success is not guaranteed, of course: Dancers can also fall ill with dementia at some point.